One sleep-promoting supplement I would recommend is cannabidiol or CBD. CBD, one of the main cannabinoids in the cannabis plant, interacts with the endocannabinoid system which helps regulate many processes in the body. While difficulty sleeping may be due to a variety of reasons, if it is caused by factors such as anxiety CBD may be beneficial. Research shows that CBD can have a calming effect, which can help reduce stress and improve sleep quality. Furthermore, if chronic pain is interrupting sleep, CBD has also been shown to help relieve pain and thereby aid in sleep. CBD may also interact with receptors in the brain that govern sleep-wake cycles, promoting sleep directly.
Another sleep-promoting supplement I would recommend is melatonin. The body produces melatonin naturally, with levels dipping in the morning and rising in the evening to promote the body’s sleep-wake cycles. Given melatonin’s role in regulating the circadian rhythm and signaling the body, it is time to sleep, supplements of this hormone can help facilitate the transition to sleep and promote consistent rest. This may be the case for individuals managing jet lag, insomnia, or wanting to improve sleep efficacy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/
https://pubmed.ncbi.nlm.nih.gov/28349316/
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273450/